Column of Hope

Chiari and Syringomyelia Research Foundation - Working toward a life without pain.

Our Mission: Searching for better understanding, treatments, and cures for Chiari malformation, syringomyelia, neuropathic pain, spinal cord injury and related conditions.

Research Update - May 9, 2023

Column of Hope is happy to announce the publication of, “Current Understanding of the Anatomy, Physiology, and Magnetic Resonance Imaging of Neurofluids: Update From the 2022 “ISMRM Imaging Neurofluids Study group” Workshop in Rome,” which we are a contract grant sponsor of.

The paper is the result of the International Society for Magnetic Resonance in Medicine (ISMRM) Workshop on Neurofluids: Anatomy, Physiology & Imaging, held at Sapienza University in Rome, Italy in September 2022. This is part of Column of Hope’s initiative for... Read More



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A normal brain and spinal cord.
Chiari malformation and Syringomyelia.

What is Chiari Malformation?

Chiari I malformation is when the back of the skull is abnormally small. When this happens there is not enough room for the brain to fit in the skull properly and part of the brain is forced out of the skull into the spinal cord. Learn more

What is Syringomyelia?

Syringomyelia is a neurological disorder in which a cyst or cavity forms in the spinal cord. The cyst is called a syrinx and can expand and elongate over time, destroying the spinal cord. Learn more

What is Neuropathic Pain?

Neuropathic pain occurs when there is a malfunction in the part of the nervous system that tells the brain that tissue is injured. While there may be no injury to the tissue where the pain exists, the nervous system tells the brain that there is damage, causing pain. Learn more

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